How to take LYNPARZA

To get the most from your treatment, always take LYNPARZA exactly as your physician tells you

What should I tell my healthcare provider before taking LYNPARZA?

Before you take LYNPARZA, tell your healthcare provider about all of your medical conditions including:

  • lung or breathing problems
  • liver problems
  • kidney problems
  • are pregnant or plan to become pregnant. LYNPARZA can harm your unborn baby and may cause loss of pregnancy (miscarriage).
    • If you are able to become pregnant, your healthcare provider may do a pregnancy test before you start treatment with LYNPARZA.
    • Females who are able to become pregnant should use effective birth control (contraception) during treatment with LYNPARZA and for 6 months after receiving the last dose of LYNPARZA.
    • Talk to your healthcare provider about birth control methods that may be right for you.
    • Tell your healthcare provider right away if you become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if LYNPARZA passes into your breast milk. Do not breastfeed during treatment and for 1 month after receiving the last dose of LYNPARZA. Talk to your healthcare provider about the best way to feed your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking LYNPARZA and certain other medicines may affect how LYNPARZA works and may cause side effects. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

How should you take LYNPARZA?

Make taking LYNPARZA a part of your daily routine by working with your caregiver or healthcare provider to establish a medication schedule that works best for you. To get the most from your treatment, always take LYNPARZA exactly as your healthcare provider tells you.

Your healthcare provider may temporarily stop treatment with LYNPARZA or change your dose of LYNPARZA if you have side effects. Be sure to talk to your healthcare provider about any reactions you experience while taking LYNPARZA.

Take 8 LYNPARZA capsules (50 mg each) by mouth twice a day (16 capsules daily).

LYNPARZA™ (olaparib) Dosing Information
  • Swallow LYNPARZA capsules whole
  • Do not chew, dissolve, or open the capsules
  • Do not take LYNPARZA capsules if they look damaged or show signs of leakage

If you miss a dose, take the next one at the usual scheduled time. Do not take an extra dose to make up for the one you missed

If you take too much LYNPARZA, call your healthcare provider or go to the nearest emergency room right away.

What should you avoid while taking LYNPARZA?

Avoid grapefruit, grapefruit juice and Seville oranges during treatment as they may increase the levels of LYNPARZA in your blood.

Possible Side Effects of LYNPARZA

Find out what patients can expect while on treatment

Learn more

What is LYNPARZA?

Learn more about LYNPARZA and how it is thought to work

Learn more

INDICATION

LYNPARZA is a prescription medicine used to treat women with advanced ovarian cancer who have received previous treatment with 3 or more prior chemotherapy medicines or a combination of chemotherapy medicines for their cancer, and have a certain type of abnormal inherited BRCA gene.

Your healthcare provider will perform a test to make sure that LYNPARZA is right for you.

Please see Important Safety Information below.

IMPORTANT SAFETY INFORMATION

There are no contraindications (a condition in which the treatment should not be used) for LYNPARZA.

LYNPARZA may cause serious side effects that can lead to death including bone marrow problems and lung problems. Some people who have..Read More ovarian cancer or who have received previous treatment with chemotherapy, radiotherapy or certain other medicines for their cancer have developed bone marrow problems called Myelodysplastic syndrome (MDS) or Acute Myeloid Leukemia (AML) during treatment with LYNPARZA. If you develop MDS or AML, your healthcare provider will stop treatment with LYNPARZA.

Symptoms of low blood cell counts are common during treatment with LYNPARZA, but can be a sign of serious bone marrow problems, including MDS or AML. Symptoms to discuss with your healthcare provider include weakness, weight loss, fever, frequent infections, blood in your urine/stool, shortness of breath, feeling very tired, and bruising or bleeding more easily.

You will undergo blood tests before, and every month during, treatment with LYNPARZA to monitor your blood cell counts. Weekly blood tests will be performed if you have low blood cell counts that last a long time. Your healthcare provider may stop treatment with LYNPARZA until your blood cell counts improve.

Tell your healthcare provider if you have any new or worsening symptoms of lung problems, including shortness of breath, fever, cough, or wheezing. Your healthcare provider may do a chest x-ray if you have any of these symptoms. Your healthcare provider may temporarily or completely stop treatment if you develop pneumonitis (inflammation of the lungs).

Before you take LYNPARZA, tell your healthcare provider about all of your medical conditions including:

  • lung or breathing problems
  • liver problems
  • kidney problems
  • are pregnant or plan to become pregnant. LYNPARZA can harm your unborn baby and may cause loss of pregnancy (miscarriage).
    • If you are able to become pregnant, your healthcare provider may do a pregnancy test before you start treatment with LYNPARZA.
    • Females who are able to become pregnant should use effective birth control (contraception) during treatment with LYNPARZA and for 6 months after receiving the last dose of LYNPARZA.
    • Talk to your healthcare provider about birth control methods that may be right for you.
    • Tell your healthcare provider right away if you become pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if LYNPARZA passes into your breast milk. Do not breastfeed during treatment and for 1 month after receiving the last dose of LYNPARZA. Talk to your healthcare provider about the best way to feed your baby.

Avoid grapefruit, grapefruit juice and Seville oranges during treatment as they may increase the levels of LYNPARZA in your blood.

The most common side effects are anemia, nausea or vomiting, tiredness or weakness, diarrhea, indigestion or heartburn, headache, loss of appetite, changes in how food tastes, changes in kidney function blood tests, sore throat or runny nose, upper respiratory infection, cough, pain in the joints, muscles, and back, rash, and pain or discomfort in the stomach area.

These are not all the possible side effects of LYNPARZA. For more information, ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088 1-800-FDA-1088.

Please see complete Prescribing Information, including Patient Information (Medication Guide).

The information on this Web site should not take the place of talking with your doctor or healthcare professional. If you have any questions about your condition, or if you would like more information about LYNPARZA, talk to your doctor or pharmacist. Only you and your healthcare professional can decide if LYNPARZA is right for you.