See how LYNPARZA helps maintain more of what matters

Linda had a plan after she finished chemotherapy for her recurrent ovarian cancer. Watch how LYNPARZA helps her along the way.

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Watch Linda's LYNPARZA journey*

Help keep recurrent ovarian cancer from coming back or getting worse

If you’ve finished chemotherapy for your recurrent ovarian cancer, you may be wondering…

Discuss LYNPARZA with your Doctor

If you find yourself asking these questions, consider talking to your doctor about using a maintenance treatment like LYNPARZA. Rather than waiting for your cancer to potentially return, maintenance treatment can be used once you've responded to chemotherapy to help maintain the response you've seen.

LYNPARZA was tested in clinical studies

LYNPARZA is a maintenance treatment that can help maintain your response

LYNPARZA is used to treat women who have recurrent ovarian cancer that has responded to treatment with platinum-based chemotherapy, regardless of whether or not they have an inherited BRCA mutation. Several studies have tested the safety and effectiveness of LYNPARZA as a maintenance treatment.

In a study of 265 women with platinum-sensitive recurrent ovarian cancer, with or without a BRCA mutation, LYNPARZA delayed the progression of cancer by a median of:

8.4 months vs 4.8 months for patients who were given placebo

In a study of 295 women with platinum-sensitive recurrent ovarian cancer, with an inherited BRCA mutation, LYNPARZA delayed the progression of cancer by a median of:

19.1 months vs 5.5 months for patients who were given placebo

Possible side effects of LYNPARZA

When choosing a treatment for recurrent ovarian cancer, it’s important to consider the safety. Common side effects may include nausea or vomiting, tiredness or weakness, diarrhea, headache, changes in kidney function blood tests, low number of platelets, changes in the way food tastes, loss of appetite, low number of red or white blood cells, mouth sores, and respiratory infections.

Some adverse events may go away over time. Your doctor can help you manage side effects.

Talk to your doctor to see if LYNPARZA is right for you.

Talk to your doctor to see if LYNPARZA is right for you.

Important Safety Information

WHAT IS LYNPARZA?

LYNPARZA is a prescription medicine used to treat adults:

  • who have ovarian cancer, fallopian tube cancer, or primary peritoneal cancer, when the cancer has come back. LYNPARZA is used after the cancer has responded to treatment with platinum-based chemotherapy
    or
  • who have advanced ovarian cancer with a certain type of abnormal inherited BRCA gene, and have received treatment with 3 or more prior types of chemotherapy medicines. Your health care provider will perform a test to make sure that LYNPARZA is right for you

It is not known if LYNPARZA is safe and effective in children.

IMPORTANT SAFETY INFORMATION

LYNPARZA may cause serious side effects, including:

Bone marrow problems called Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML). Some people who have ovarian cancer or breast cancer and who have received previous treatment with chemotherapy, radiotherapy, or certain other medicines for their cancer have developed MDS or AML during treatment with LYNPARZA. MDS or AML may lead to death. If you develop MDS or AML, your health care provider will stop treatment with LYNPARZA.

Symptoms of low blood cell counts are common during treatment with LYNPARZA, but can be a sign of serious bone marrow problems, including MDS or AML. Symptoms may include weakness, weight loss, fever, frequent infections, blood in urine or stool, shortness of breath, feeling very tired, bruising or bleeding more easily.

Your health care provider will do blood tests to check your blood cell counts:

  • before treatment with LYNPARZA
  • every month during treatment with LYNPARZA
  • weekly if you have low blood cell counts that last a long time. Your health care provider may stop treatment with LYNPARZA until your blood cell counts improve.

Lung problems (pneumonitis). Tell your health care provider if you have any new or worsening symptoms of lung problems, including shortness of breath, fever, cough, or wheezing. Your health care provider may do a chest x-ray if you have any of these symptoms. Your health care provider may temporarily or completely stop treatment if you develop pneumonitis. Pneumonitis may lead to death.

Before taking LYNPARZA, tell your health care provider about all of your medical conditions, including if you:

  • have lung or breathing problems
  • have kidney problems
  • are pregnant, become pregnant, or plan to become pregnant. LYNPARZA can harm your unborn baby and may cause loss of pregnancy (miscarriage).
    • If you are able to become pregnant, your health care provider may do a pregnancy test before you start treatment with LYNPARZA
    • Females who are able to become pregnant should use effective birth control (contraception) during treatment with LYNPARZA and for 6 months after the last dose of LYNPARZA. Talk to your health care provider about birth control methods that may be right for you
  • are breastfeeding or plan to breastfeed. It is not known if LYNPARZA passes into your breast milk. Do not breastfeed during treatment with LYNPARZA and for 1 month after receiving the last dose of LYNPARZA. Talk to your health care provider about the best way to feed your baby during this time.

Tell your health care provider right away if you become pregnant.

Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking LYNPARZA and certain other medicines may affect how LYNPARZA works and may cause side effects.

How should I take LYNPARZA?

  • Take LYNPARZA tablets exactly as your health care provider tells you
  • Your health care provider may temporarily stop treatment with LYNPARZA or change your dose of LYNPARZA if you experience side effects
  • Do not take more than 4 LYNPARZA tablets in 1 day. If you have any questions about LYNPARZA, talk to your health care provider or pharmacist
  • Take LYNPARZA by mouth 2 times a day
  • Each dose should be taken about 12 hours apart
  • Swallow LYNPARZA tablets whole. Do not chew, crush, dissolve, or divide the tablets
  • Take LYNPARZA with or without food
  • If you miss a dose of LYNPARZA, take your next dose at your usual scheduled time
  • Do not take an extra dose to make up for a missed dose
  • If you take too much LYNPARZA, call your health care provider or go to the nearest hospital emergency room right away

What should I avoid while taking LYNPARZA?

Avoid grapefruit, grapefruit juice, Seville oranges, and Seville orange juice during treatment with LYNPARZA since they may increase the level of LYNPARZA in your blood.

LYNPARZA may cause serious side effects (see above). The most common side effects of LYNPARZA are:

  • nausea or vomiting. Tell your health care provider if you get nausea or vomiting. Your health care provider may prescribe medicines to treat these symptoms
  • low number of red or white blood cells
  • tiredness or weakness
  • sore throat or runny nose
  • diarrhea
  • joint, muscle, and back pain
  • headache
  • constipation
  • changes in the way food tastes
  • loss of appetite
  • mouth sores
  • respiratory infections
  • changes in kidney function blood test
  • low number of platelets
  • indigestion or heartburn

These are not all the possible side effects of LYNPARZA. Call your health care provider for medical advice about side effects.

You may report side effects related to AstraZeneca products by clicking here.

Please see complete Prescribing Information, including Patient Information (Medication Guides).