The goal of treating advanced cancer is usually to shrink the cancer and control its growth for as long as possible. At some point, you may receive chemotherapy. This type of treatment can be used to reach almost all areas of the body and may be given intravenously or orally. Your cancer may respond to chemotherapy by shrinking or disappearing.
Unfortunately, more than 70% of women will see their ovarian cancer return within 3 years after chemotherapy. That’s why your health care provider may choose between 2 approaches after treatment has ended: a watch-and-wait approach or an active maintenance approach, like LYNPARZA.
This approach means that your health care provider will closely monitor you with blood tests and possibly scans to see if the cancer returns or grows. Throughout the duration of this approach, you will not be taking medication to keep your cancer from coming back.
Another option your health care provider may choose is an active approach called maintenance treatment. Your health care provider will monitor you while taking this prescription medication to see if the cancer returns or grows. LYNPARZA is a type of oral maintenance treatment known as a targeted therapy, which is different from the chemotherapy you may have received in the past.
Both may help extend the time you spend progression free.
Unlock the potential for more time progression free. Ask your health care provider about LYNPARZA: a type of active maintenance treatment to help keep your cancer from growing or returning.
Your health care provider will help guide you through the process of treatment to see which medicine may be best for you.
You could be eligible for an active approach. Why wait to talk to your doctor about LYNPARZA?
LYNPARZA is not chemotherapy; it’s a targeted therapy called a PARP inhibitor.
LYNPARZA is a maintenance treatment for women regardless of whether or not they have a BRCA mutation.
LYNPARZA is taken orally with 2 tablets (150 mg each) taken 2 times a day (300 mg per dose), totaling 4 tablets each day.
PARP=poly (ADP-ribose) polymerase.
Ovarian cancer is diagnosed.
Treated with chemotherapy.
Cancer returns or grows.
Treated with chemotherapy.
Cancer is responding to chemotherapy.
May be eligible for treatment with LYNPARZA.
After chemotherapy, talk to your doctor about an active maintenance approach with LYNPARZA.
LYNPARZA is a prescription medicine used to treat adults who have:
It is not known if LYNPARZA is safe and effective in children.
LYNPARZA may cause serious side effects, including:
Bone marrow problems called Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML). Some people who have ovarian cancer or breast cancer and who have received previous treatment with chemotherapy, radiotherapy, or certain other medicines for their cancer have developed MDS or AML during treatment with LYNPARZA. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with LYNPARZA.
Symptoms of low blood cell counts are common during treatment with LYNPARZA, but can be a sign of serious bone marrow problems, including MDS or AML. Symptoms may include weakness, weight loss, fever, frequent infections, blood in urine or stool, shortness of breath, feeling very tired, bruising or bleeding more easily.
Your healthcare provider will do blood tests to check your blood cell counts:
Lung problems (pneumonitis). Tell your healthcare provider if you have any new or worsening symptoms of lung problems, including shortness of breath, fever, cough, or wheezing. Your healthcare provider may do a chest x-ray if you have any of these symptoms. Your healthcare provider may temporarily or completely stop treatment if you develop pneumonitis. Pneumonitis may lead to death.
Before taking LYNPARZA, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking LYNPARZA and certain other medicines may affect how LYNPARZA works and may cause side effects.
How should I take LYNPARZA?
What should I avoid while taking LYNPARZA?
Avoid grapefruit, grapefruit juice, Seville oranges, and Seville orange juice during treatment with LYNPARZA since they may increase the level of LYNPARZA in your blood.
LYNPARZA may cause serious side effects. The most common side effects of LYNPARZA are:
These are not all the possible side effects of LYNPARZA. Call your healthcare provider for medical advice about side effects.
You may report side effects related to AstraZeneca products by clicking here.
Please click here for complete Prescribing Information, including Patient Information (Medication Guide).