Discover the meaning of some of the terms and phrases used in this website.
If you have previously received chemotherapy or hormonal therapy, active treatment may be used to shrink or slow the growth of your cancer. LYNPARZA can be used in certain people as active treatment.
A treatment used after you have responded to chemotherapy. It can help extend the time without cancer growing or returning. LYNPARZA can be used in certain people as maintenance therapy.
A type of protein that repairs DNA damage in cells.
A targeted therapy that stops PARP from repairing DNA damage. LYNPARZA is a PARP inhibitor.
A type of cancer treatment that works by targeting specific changes in cancer cells to keep them from growing or spreading.LEARN MORE ABOUT LYNPARZA
About LYNPARZA studies
The middle number in a list of numbers arranged from lowest to highest.
A treatment that does not contain active medicine. It is usually used in clinical studies to compare against active medicines.
A phrase used to describe time spent without cancer growing or returning.
About genetic testing
Acquired BRCA mutation
A change or alteration found in the BRCA1 or BRCA2 gene that was not passed down from a family member. This is also known as a somatic mutation.
A change or alteration found in the BRCA1 or BRCA2 gene. A mutation can be inherited (germline), which means it was passed down from a family member, or acquired (somatic), which means it was not passed down.
A genomic biomarker is a measurable DNA characteristic that shows biologic processes and how you may respond to certain therapies. It may indicate the risk of a person getting a particular disease; for example, a genetic mutation.
Using a sample from your blood or saliva, this type of genetic test identifies inherited mutations.
Inherited BRCA mutation
A change or alteration found in the BRCA1 or BRCA2 gene that is passed down from your mother or father. This is also known as a germline mutation.
This type of genetic test uses a tissue sample from a tumor to find acquired and inherited mutations. It is also known as a tumor molecular test.LEARN MORE ABOUT GENETIC TESTING
About advanced ovarian cancer
Advanced ovarian cancer
Cancer that has spread outside of the ovaries.
First line of chemotherapy
A complete course of chemotherapy given as your first treatment for advanced cancer.
Second line of chemotherapy
A complete course of chemotherapy given if your ovarian cancer has returned.LEARN MORE ABOUT ADVANCED OVARIAN CANCER
About metastatic breast cancer
HER2-negative breast cancer
When breast cancer cells do not contain extra amounts of HER2 (human epidermal growth factor receptor 2).
Hormone receptor (HR)-positive
When breast cancer cells contain either estrogen or progesterone receptors, or both.
Metastatic breast cancer
Cancer that has spread to other parts of the body beyond the nearby lymph nodes, sometimes shortened to mBC.
When breast cancer cells do not contain extra amounts of HER2 receptors, or progesterone and estrogen receptors.LEARN MORE ABOUT METASTATIC BREAST CANCER